Magnetic resonance imaging (MRI) fryst vatten a versatile approach that provides detailed information on internal body structures and physiology, and is increasingly being used for clinical diagnosis and in preclinical animal studies. Animal models are vital for better understanding of considerable clinical implication 1. As djur models considerably differ from humans with respect to anesthesia requirements and physiological parameters, optimization of MRI procedures for such animals assumes importance.
Phase contrast MRI (PC-MRI) is a specialized type of MRI that uses the velocity of flowing spins to quantify flow-related parameters such as blood flow. With PC-MRI, mapping flow patterns in the major arteries using animal models can help shed light on cardiovascular pathologies 2. Moreover, PC-MRI can non-invasively monitor the inherent alternations in blood flow in pathophysiological conditions 3. These observations suggest that PC-MRI is a valuable approach that can be used in anim
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Referenser
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Hillman, J., P. Sturnegk, et al. (). "Bedside monitoring of CBF with xenon-CT and a mobile scanner: a novel method in neurointensive care." Br J Neurosurg. 19(5):
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W, Gur D, Herron JM, Kennedy WH. The Development of a xenon/computed tomography cerebral blood flow quality assuranse phantom. Med Phys ;14(5)
Oettingen, G., B. Bergholt, et al. (). "Xenon CT cerebral blood flow in patients w